Magnetized Solutions Altered the Absorbance of Tramadol Hcl: Uv-spectrophotometer Study

نویسندگان

  • Marwan S.M. Al-Nimer
  • Fezaa Sh. Neda
  • Zainab W. Abdul Lateef
چکیده

Magnetized water showed alterations in the electrolyte potential and vibration modes. This study aimed to investigate the effect of magnetic water and physiological solutions on the UV-spectra of tramadol HCl. Distilled water as well as full strength or diluted physiological solutions are magnetized by magnetic disc. Then tramadol HCl was dissolved in each magnetic and in non-magnetic solution to obtain the following final concentrations: 0, 25, 50, 100, and 200μg/mL. The pH of each solution and the absorbance (O.D.) was recorded at wavelength 271 nm. Magnetized water or physiological solutions showed alterations in pH as well as in the absorbance (O.D.) of tramadol HCl detected by ultraviolet spectra at λ271 nm. It concludes that magnetized physiological solutions adversely altered the stability of tramadol HCl.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Development of a Low Cost and Portable Light Absorbance Measurement Device for Chemical Education

This research aims to study about developing and demonstrating the low-cost and portable light absorbance measurement device for using and learning in analytical experiments. In chemistry experiments, the concentration of solutions is important for mixing the sample or making medicines. In present, a UV-spectrophotometer is commonly used to check the absorbance of solution for investigating con...

متن کامل

Complex formation between Tragacanth gum and beta-lactoglobulin in aqueous solution

Proteins and polysaccharides are common ingredients in food products. In many food formulations, proteins and polysaccharides (two major biopolymers) are used simultaneously. Understanding their interactions can help controlling physical properties and stability of formulated foods. Interactions between β-lactoglobulin (BLG) and tragacanth gum (TG) were studied in aqueous solutions at pH rangin...

متن کامل

Formulation and In-vitro Characterization of Monolithic Matrix Transdermal Systems Using Hpmc/eudragit S 100 Polymer Blends

In the present work, monolithic matrix transdermal systems containing tramadol HCl were prepared using various ratios of the polymer blends of hydroxy propyl methyl cellulose (HPMC) and Eudragit S 100 (ES) with triethyl citrate as a plasticizer. A 3 full factorial design was employed. The concentration of HPMC and ES were used as independent variables, while percentage drug release was selected...

متن کامل

Estimating total urea removal and protein catabolic rate by monitoring UV absorbance in spent dialysate.

BACKGROUND Dialysate-based, on-line measurements of Kt/V and protein catabolic rate (PCR) in dialysis patients have been considered more accurate compared with measurements on the blood side during dialysis. The primary aim of this study was to compare total removed urea (TRU) and PCR, normalized to body weight (nPCRw), obtained by three dialysate-based methods: (i) on-line ultraviolet (UV) abs...

متن کامل

Development and Application of Difference Spectrophotometric Method for the Determination of Febuxostat in Tablets

A simple, rapid, sensitive and cost effective difference spectrophotometric method have been developed for the determination of Febuxostat in its tablet dosage form. The method is based on the induced spectral changes upon changing the pH of the medium that differ in their UV spectra. Difference spectrum, obtained by keeping Febuxostat in 0.1N NaOH in reference cell and same in 0.1N HCl in samp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2010